Phenanthrene derivatives as MPGES-1 inhibitors

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20090209571A1
SERIAL NO

12227338

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention encompasses novel compounds of Formula or pharmaceutically acceptable salts thereof. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful to treat pain and/or inflammation from a variety of diseases or conditions, such as osteoarthritis, rheumatoid arthritis and acute or chronic pain. Methods of treating diseases or conditions mediated by the mPGES-1 enzyme and pharmaceutical compositions are also encompassed.

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Patent Owner(s)

Patent OwnerAddress
MERCK FROSST CANADA LTDQUEBEC CANADA QUEBEC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cote, Bernard L'lle-perrot , CA 18 171
Ducharme, Yves Montreal , CA 34 1401
Frenette, Richard Laval , CA 36 433
Friesen, Richard Kirkland , CA 33 359
Giroux, Andre Ste-anne-de-bellevue , CA 12 129
Hamel, Pierre Vimont-laval , CA 43 859
Martins, Evelyn Vaudreuil , CA 11 73

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