ABCA-1 ELEVATING COMPOUNDS AND METHODS
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United States of America Patent
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Issued Date -
Aug 13, 2009
app pub date -
Feb 6, 2009
filing date -
Feb 7, 2008
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Abstract
Disclosed are novel compounds of Formula Iuseful for treating various disease states, in particular, insulin resistance, diabetes, dyslipidemia, coronary artery disease, and inflammation. The compounds of the present invention elevate cellular expression of the ABCA-1 gene as well as increasing the level of ABCA-1 protein, which may result in an increase in HDL levels in the plasma of a mammal, in particular humans.
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