METHOD FOR PRODUCTION OF CYTOCHROME P450 WITH N-TERMINAL TRUNCATED P450 REDUCTASE
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
N/A
app pub date -
Nov 4, 2008
filing date -
May 5, 2006
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The present invention provides a P450 reductase lacking N-terminal amino acids, as well as a nucleic acid encoding the P450 reductase. When co-expressed with a cytochrome P450, the P450 reductase increases the activity and/or expression of the cytochrome P450 compared to the activity and/or expression of the cytochrome P450 when co-expressed with a wild type P450 reductase. The invention also provides the use of certain promoters to increase expression of cytochrome P450, P450 reductase and/or b5, as well as the use of protease-deficient strains of yeast in which to express the proteins of the present invention.
First Claim
Other Claims data not available
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- C07H Class
- 0 % this patent is cited more than
- 16 Age