Semi-Synthetic GLP-1 Peptide-FC Fusion Constructs, Methods and Uses
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United States of America Patent
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Issued Date -
Jul 16, 2009
app pub date -
Nov 3, 2008
filing date -
Nov 2, 2007
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Abstract
The invention relates to semi-synthetic biologic molecules which are conjugates of GLP-1 peptides and human multimeric proteins or protein fragments, such as an antibody Fc joined by a non-peptidyl bond. The constructs demonstrate biological activity and are useful making therapeutic compositions and therapeutic formulations for use in treating diseases characterized by lack of glycemic control.
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