Methods of Detecting Inhibitors of VIF-Mediated APOBEC3G Degradation and HIV
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United States of America Patent
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Issued Date -
Jul 9, 2009
app pub date -
Mar 24, 2008
filing date -
Mar 23, 2007
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Abstract
The invention comprises methods and cell lines for assaying APOBEC3G degradation and methods for identifying inhibitors of APOBEC3G degradation. The invention also provides methods of identifying inhibitors of HIV infection. The methods of the invention are useful for identifying inhibitors of viral infection, in particular, the methods of the invention are useful for treating retroviral infection.
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