RADIOLABELED DERIVATIVES OF POTENT CHYMASE INHIBITORS

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United States of America Patent

APP PUB NO 20090169475A1
SERIAL NO

12338426

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Abstract

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Methods of imaging tissue of a mammal which expresses chymase include administering to the mammal an effective amount of a radiolabeled chymase inhibitor. Radiopharmaceuticals that may be used in diagnostic imaging and therapeutic treatment of disease characterized by expression of chymase have the structure of Formula I:

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Patent Owner(s)

Patent OwnerAddress
MOLECULAR INSIGHT PHARMACEUTICALS INCONE WORLD TRADE CENTER 47TH FLOOR SUITE J NEW YORK NY 10007

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Babich, John W Cambridge , US 88 1375
Eckelman, William C Cambridge , US 9 159
Joyal, John Melrose , US 12 414
Zimmerman, Craig Topsfield , US 40 957

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