COMPOSITIONS COMPRISING HDAC INHIBITORS AND METHODS OF THEIR USE IN RESTORING STEM CELL FUNCTION AND PREVENTING HEART FAILURE

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United States of America Patent

SERIAL NO

12325816

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Abstract

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The invention provides compositions of histone deacetylase (HDAC) inhibitors and progenitor cells useful for treating heart failure in a subject. The invention also provides methods of restoring progenitor cell function to aged progenitor cells and methods for enhancing progenitor cell proliferation and/or differentiation using HDAC inhibitors.

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Patent Owner(s)

Patent OwnerAddress
NEW YORK MEDICAL COLLEGE40 SUNSHINE COTTAGE ROAD VALHALLA NY 10595

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Anversa, Piero Boston , US 38 908
Kajstura, Jan Brookline , US 14 347
Leri, Annarosa Boston , US 20 357

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