Immunoglobulin Cleavage Fragments as Disease Indicators and Compositions for Detecting and Binding Such
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United States of America Patent
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Issued Date -
Jun 18, 2009
app pub date -
Aug 4, 2008
filing date -
Aug 10, 2007
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Abandoned
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Abstract
The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG breakdown products retaining antigen binding but having lost effector functions.
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