Stable Aqueous Systems Comprising Proteins

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United States of America Patent

APP PUB NO 20090148406A1
SERIAL NO

11994408

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An aqueous system comprises a protein and one or more stabilising agents, characterised in that (i) the one or more stabilising agents have ionisable groups capable of exchanging protons with the protein and with the ionised products of water dissociation; (ii) the ionisable groups include first groups that are positively charged when protonated and uncharged when deprotonated, and second groups that are uncharged when protonated and negatively charged when deprotonated; and (v) the pH of the composition is within a range of protein stability that is at least 50% of the maximum stability of the protein with respect to pH.

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Patent Owner(s)

Patent OwnerAddress
ARECOR LIMITEDLITTLE CHESTERFORD SAFFRON WALDEN CB10 1XL

International Classification(s)

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  • 2006 Application Filing Year
  • A61K Class
  • 9598 Applications Filed
  • 4848 Patents Issued To-Date
  • 50.52 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2006200720082009201020112012201320142015201620172018201920202021202220230255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jezek, Jan Wellingborough , GB 73 261

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  • 17 Citation Count
  • A61K Class
  • 64.41 % this patent is cited more than
  • 16 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges509253082135216811765452724174301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +02004006008001000120014001600180020002200240026002800

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