METHODS AND APPARATUSES FOR REDUCING EFFECTS OF MOLECULE ADSORPTION WITHIN MICROFLUIDIC CHANNELS

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United States of America Patent

APP PUB NO 20090145201A1
SERIAL NO

11719530

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Abstract

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Microfluidic methods and apparatuses for reducing the effects of sample adsorption inside microfluidic chann are provided. According to one embodiment, a microfluidic chip (MFC) comprising an analysis channel (AC) having a cross-sectional area at least two times larger than a cross-sectional area of a microscale channel in fluid communication with the analysis channel is provided that reduces the effects of compound adsorption on data analysis. According to another embodiment, methods for reducing the effect of molecule adsorption to a channel wall (W) on analysis of a reaction in a microfluidic device and methods for making concentration dependent measurements in a microfluidic device are provided which utilize novel microfluidic chips disclose herein.

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Patent Owner(s)

Patent OwnerAddress
AB SCIEX LLC500 OLD CONNECTICUT PATH FRAMINGHAM MA 01701

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Crenshaw, Hugh C Durham , US 18 426
Pettigrew, Kenneth I Sutherland , US 3 46

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