MICROARRAYS FOR GENOTYPING AND METHODS OF USE
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United States of America Patent
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Issued Date -
Jun 4, 2009
app pub date -
Feb 20, 2006
filing date -
Nov 15, 2005
priority date (Note) -
Abandoned
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Abstract
The present invention provides a microarray for detecting a genotype at a polymorphic site in a plurality of nucleic acid samples, comprising a first set of nucleic acid fragments derived from the samples and a second set of nucleic acid fragments derived from a plurality of references immobilized thereon. The invention also provides a microarray comprising a set of nucleic acid fragments immobilized on the surface of the microarray, wherein the nucleic acid fragments are derived from the samples by amplifying a region in the sample containing the polymorphism through asymmetric PCR amplification. Methods of using and making the microarrays are also provided.
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