Method for Cleaving Cervimycin Monoesters

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20090142809A1
SERIAL NO

12084721

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The invention relates to a method for cleaving cervimycin esters. An object of the invention to convert in a simple manner the cervimycin esters which are less active but formed in larger quantity into the highly active cervimycin K that occurs as a minor component in the preparation by fermentation, is achieved by preparing unesterified cervimycins from cervimycin esters with di- or monomethylated malonic acids, by ester cleavage effected by at least one esterolytic enzyme at temperatures of 20° C. to 75° C. and a pH of pH 5.0 to 10.0, preferably pH 6.0 to 9.0.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
FRIEDRICH-SCHILLER-UNIVERSITAET JENAJENA
LEIBNIZ-INSTITUT FUER NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E V HANS-KNOELL-INSTITUT-(HKI)BEUTENBERGSTRASSE 11A D-07745 JENA

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bardl, Bettina Jena , DE 1 0
Herold, Kerstin Jena , DE 2 0
Hertweck, Christian Leipzig , DE 11 2
Horn, Uwe Rottleben , DE 38 1087
Muller, Peter-Jurgen Jena , DE 3 15
Ozegowski, Jorg-Hermann Jena , DE 1 0
Peschel, Gundela Jena , DE 3 19
Siering, Armin Jena , DE 1 0

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation