METHOD OF CAPPING OLIGONUCLEIC ACID
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United States of America Patent
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Issued Date -
May 28, 2009
app pub date -
Feb 26, 2007
filing date -
Feb 27, 2006
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a method for producing an oligonucleic acid derivative characterized by using a phenoxyacetic acid derivative anhydride as an acylating agent and a pyridine derivative as the acylation reaction activator, in a capping step for protecting the 5′-hydroxyl group of a ribose of an oligonucleic acid derivative.
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