Novel compositions and methods for identification, assessment, prevention, and therapy of ovarian cancer

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United States of America Patent

SERIAL NO

12313196

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Abstract

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The present invention is directed to the identification of markers that can be used to determine whether ovarian cancer is sensitive or resistant to a therapeutic agent. In particular, the present invention is directed to the use of certain combinations of markers, wherein the expression of the markers correlates with sensitivity or resistance to a therapeutic agent. Thus, by examining the expression of the individual markers of a marker set, also referred to as the expression profile of the marker set, it is possible to determine whether a therapeutic agent, or combination of agents, will be most likely to reduce the growth rate of the ovarian cancer.

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Patent Owner(s)

Patent OwnerAddress
MILLENNIUM PHARMACEUTICALS INCCAMBRIDGE MA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bast, Robert C JR Houston, US 5 72
Clark, Edwin A Ashland, US 12 81
Damokosh, Andrew I West Hortford, US 9 177
Hartmann, Lynn Rochester, US 6 7
Lartchouk, Natalia Wayland, US 1 0
Lu, Karen Houston, US 10 54
Mills, Gordon B Houston, US 40 399
Stec, James J II Plymouth, US 1 0

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