Automated Enumeration and Characterization of Circulating Melanoma Cells in Blood

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United States of America Patent

APP PUB NO 20090136946A1
SERIAL NO

12254188

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The CellTracks® System provides a system to enumerate circulating melanoma cells in blood. The system immunomagnetically concentrates epithelial cells, fluorescently labels the cells and identifies and quantifies circulating melanoma cells. The absolute number of circulating melanoma cells detected in the peripheral blood tumor load is, in part, a factor in prediction of survival, time to progression, and response to therapy. Diagnosis and monitoring of melanoma has been limited by the inability to monitor circulating melanoma cells. The present invention provides a method to enumerate circulating melanoma cells in blood samples. Accordingly, this technology provides a means and device for monitoring disease progression in patients with melanoma.

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Patent Owner(s)

Patent OwnerAddress
JANSSEN DIAGNOSTICS LLC700 US HIGHWAY 202 RARITAN NJ USA 08869

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CONNELLY, Mark Carle Doylestown, US 16 389
Rao, Galla Chandra Princeton Junction, US 33 2508
Terstappen, Leon WMM Amsterdam, NL 37 2074

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