TRANSDERMAL PATCH CONTAINING RASAGILINE FOR TREATMENT OR PROPHYLAXIS OF NERVOUS SYSTEM DISEASE AND ITS PREPARATION PROCESS
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United States of America Patent
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Issued Date -
May 28, 2009
app pub date -
Mar 6, 2007
filing date -
Mar 6, 2006
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a rasagiline transdermal patch for treatment or prophylaxis of nervous system diseases, in which the patch comprises an inert backing layer chemically inert to substrate ingredients, a substrate layer comprising rasagiline or a pharmaceutically acceptable salt thereof, and a protective layer to be peeled off before use. The substrate layer is an adhesive system comprising an organic polymer material as basis and an inorganic or organic material as filler, and a plurality of micro-reservoirs containing rasagiline. The substrate further comprises one or more substances for enhancing the transdermal absorption of rasagiline, in which the above organic polymer material in the substrate is used for the reservoir of rasagiline and as adhesive.
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