RAF Inhibitors and Uses Thereof

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United States of America Patent

SERIAL NO

12356097

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Abstract

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The present invention provides imidazooxazole and imidazothiazole compounds and their synthesis. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAFV600E. The compounds are useful for the treatment of cell proliferative disorders such as cancer.

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Patent Owner(s)

Patent OwnerAddress
ARQULE INC19 PRESIDENTIAL WAY WOBURN MA 01801-5140

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ali, Syed M North Andover, US 53 993
Ashwell, Mark A Carlisle, US 57 477
Brassard, Chris J Somerville, US 2 15
Carazza, Rebecca J Winchester, US 2 15
Filikov, Anton Stoneham, US 18 279
France, Dennis S Cambridge, US 6 39
Hutchins, Patrick M Denver, US 2 15
Lapierre, Jean Marc Pelham, US 9 25
Link, Jeff S Londonderry, US 2 15
Liu, Yanbin Acton, US 50 440
Namdev, Nivedita D Westford, US 3 16
Nicewonger, Robb B Tyngsboro, US 2 15
Tandon, Manish Framingham, US 33 359
Wu, Hui Malden, US 159 1493

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