Method of Estimating Effect of Test Chemical on Living Organisms
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United States of America Patent
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Issued Date -
May 28, 2009
app pub date -
Sep 22, 2006
filing date -
Sep 22, 2005
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Abandoned
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Abstract
A method of predicting an effect of a test chemical on living organisms, which comprises:
- a step of administering a plurality of chemicals whose effects on living organisms are known, to respective chemical dosed groups, administering a test chemical to a test chemical dosed group, collecting proteins from each group after a definite period of time, separating the proteins by two-dimensional gel electrophoresis, measuring the signal intensities of spots of the proteins and modified proteins formed therefrom, and calculating a signal intensity ratio of at least two spots, and
- a step of comparing the signal intensity ratio of test chemical dosed group with the signal intensity ratio of each chemical dosed group.
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