Immune Agglutination Reagent Kit and Method of Measuring Antigen
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United States of America Patent
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Issued Date -
May 7, 2009
app pub date -
Mar 30, 2007
filing date -
Mar 31, 2006
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Abstract
In cases of poor reaction efficiency with the antibody due to inadequate number of epitopes or steric hindrance caused by epitopes being close to each other, this invention provides a direct method of efficiently measuring antigen in a given specimen without the need of pretreating it. Two types of monoclonal antibodies that recognize different epitopes are individually sensitized on separate latex. The specimen and one latex sensitized monoclonal antibody reagent are reacted to produce a reaction solution which is then reacted with the other latex sensitized monoclonal antibody reagent. The antigen can thus be directly measured in an efficient and highly sensitive way without pretreating it.
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