INHIBITION OF GLYCOGEN SYNTHASE KINASE 3 BETA IN ARTERIAL REPAIR AND STENT RE-ENDOTHELIALIZATION

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United States of America Patent

APP PUB NO 20090117090A1
SERIAL NO

12263870

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A device having a kinase inhibitor for treating or preventing vascular disease in a subject and a method of treating a subject therewith, is disclosed. The device can be a stent coated with the kinase inhibitor. The kinase inhibitor can be a glycogen synthase kinase (GSK) inhibitor, such as a GSK-3β inhibitor. Coronary artery disease and ischemic heart disease can be treated.

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Patent Owner(s)

Patent OwnerAddress
OTTAWA HEART INSTITUTE RESEARCH CORPORATION40 RUSKIN STREET OTTAWA ONTARIO K1Y 4W7

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HIBBERT, Benjamin Ottawa, CA 1 0
MA, Xiaoli Nepean, CA 34 469
O'BRIEN, Edward RM Ottawa, CA 4 2

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