MINOR GROOVE BINDER - ENERGY TRANSFER OLIGONUCLEOTIDES AND METHODS FOR THEIR USE

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United States of America Patent

APP PUB NO 20090111100A1
SERIAL NO

11929884

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Abstract

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The incorporation of a minor groove binder spaced close to one member of a matched FRET set in a minor groove binder-oligonucleotide conjugate significantly reduces background fluorescence of a FRET probe or pair of probes and, consequently, increases the S/B ratios. Fluorescent-labeled probes are useful in carrying out hybridization, multiplex nucleic acid detection, and other procedures.

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Patent Owner(s)

Patent OwnerAddress
ELITECH HOLDING B V6956 AV SPANKEREN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lukhtanov, Eugene Bothell , US 6 85
Scarr, Noah Seattle , US 14 35

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