PROCESS FOR THE PRODUCTION OF TRANS-10, CIS 12 OCTADECADIENOIC ACID
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United States of America Patent
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Issued Date -
Apr 23, 2009
app pub date -
Nov 29, 2006
filing date -
Dec 24, 2005
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Abandoned
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Abstract
The present application is directed to a process for the production of trans-10, cis-12 conjugated linoleic acid in a transgenic microorganism comprising the steps of: (a) introducing into said microorganism at least one nucleic acid molecule encoding a trans-10, cis-12 conjugated linoleic acid isomerase, (b) culturing the transgenic microorganism obtained under (a), (c) inducing the production of trans-10, cis-12 conjugated linoleic acid by adding linoleic acid to the culture, (d) incubating the induced culture for at least 12 hours, and (e) isolating the conjugated linoleic acid from the culture media and/or transgenic microorganism.
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