PHL P 1 Allergen Derivative

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United States of America Patent

APP PUB NO 20090098167A1
SERIAL NO

12299292

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Method for producing derivatives of wild-type protein allergen Phl p 1 with reduced allergenic activity compared to the wild-type allergen, comprising the following steps: providing wild-type protein allergen Phl p 1, fragmenting said wild-type protein allergen into at least three fragments, wherein at least one fragment of said at least three fragments comprises at least one T-cell epitope and said at least three fragments have a reduced allergenic activity or lack allergenic activity and rejoining said at least three fragments in an order differing from the order of the fragments in the wild-type allergen.

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Patent Owner(s)

Patent OwnerAddress
BIOMAY AG1090 WIEN
ALLERGOPHARMA JOACHIM GANZER KGHERMANN KORNER-STRASSE 52 REINBEK 21465

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ball, Tanja Vienna , AT 4 15
Linhart, Birgit Weissenkirchen , AT 11 22
Lupinek, Christian Vienna , AT 2 2
Stocklinger, Angelika Salzburg , AT 1 2
Thalhamer, Josef Lamprechtshausen , AT 7 56
Valent, Peter Vienna , AT 34 53
Valenta, Rudolf Theresienfeld , AT 60 144

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