Methods for selective targeting

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United States of America Patent

PATENT NO 8318640
APP PUB NO 20090093393A1
SERIAL NO

12099632

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A selective targeting method is disclosed comprising contacting a library of ligands, particularly a peptide library, with an anti-target to allow the ligands to bind to the anti-target; separating the non-binding ligands from the anti-target bound ligands, contacting the non-binding anti-target ligands with a target allowing the unbound ligands to bind with the target to form a target-bound ligand complex; separating the target-bound ligand complex from ligands which do not bind to the target, and identifying the target-bound ligands on the target-bound ligand complex wherein the target-bound ligands have a KD in the range of about 10−7 to 10−10 M. Additionally claimed are the ligands identified according to the method.

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Patent Owner(s)

Patent OwnerAddress
DANISCO US INC925 PAGE MILL ROAD PALO ALTO CA 94304

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Yiyou San Jose, US 36 253
Estell, David A San Mateo, US 246 1784
Murray, Christopher J Soquel, US 131 2282
Tijerina, Pilar San Diego, US 8 131

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