Method for Detecting p53 Dysfunction, Method for Molecular Diagnosis of Cancer and Method for Evaluating Compound Effective in Treating Cancer
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United States of America Patent
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Issued Date -
Apr 9, 2009
app pub date -
Feb 1, 2006
filing date -
Feb 1, 2005
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Abandoned
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Abstract
The present invention relates to methods for detecting a dysfunctional cancer suppressing gene, particularly p53. In other aspects, the invention provides methods for diagnosing cell proliferative disorders such as cancer by measuring expression of a predetermined target gene. Methods of evaluating the efficacy of a test compound to treat a cell proliferative disorder are also included. Such methods generally rely on the expression levels of a predetermined or targeted gene.
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