Synthesis of 6,7-Dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides

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United States of America Patent

SERIAL NO

12329193

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Abstract

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Disclosed is a multi-step process for preparing a compound of Formula I:are as defined herein. The compounds of formula I inhibit the binding of human intercellular adhesion molecules to the Leukointegrins. As a result, these compounds are useful in the treatment of inflammatory and immune cell-mediated diseases.

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Patent Owner(s)

Patent OwnerAddress
BOEHRINGER INGELHEIM INTERNATIONAL GMBHGERMANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
FRUTOS, Rogelio Perez Sandy Hook , US 10 157
KRISHNAMURTHY, Dhileepkumar Brookfield , US 28 246
KROEBER, Jutta Bingen-dietersheim , DE 7 43
NICOLA, Thomas Ingelheim , DE 31 920
NUMMY, Laurence John Newburgh , US 3 6
REEVES, Diana New Milford , US 3 0
SENANAYAKE, Chris Hugh Brookfield , US 62 559
VARSOLONA, Richard J Scotch Plains , US 29 179
WANG, Xiao-jun Danbury , US 27 1059
WIRTH, Thomas Stadecken-elsheim , DE 223 1313
XU, Yibo New Milford , US 31 226
ZHANG, Li New Milford , US 2775 40019

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