Assay method for identifying drug candidate
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United States of America Patent
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Issued Date -
Apr 2, 2009
app pub date -
Mar 30, 2005
filing date -
Mar 31, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention provides a method of identifying a drug candidate capable of removing peptide, oligopeptide, polypeptide or protein from fibril or aggregate, which includes measuring, in the presence of a test compound, the concentration of a soluble peptide, a soluble oligopeptide, a soluble polypeptide or a soluble protein in an equilibrium state in a solvent. Moreover, the present invention provides a dissolution promoter to remove peptide, oligopeptide, polypeptide or protein from fibril or aggregate, which contains the compound obtained by the identification method as an active ingredient.
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