Soluble HLA-E Molecules And Their Use For Diagnosing And Treating Pathologies
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United States of America Patent
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Issued Date -
Mar 26, 2009
app pub date -
Dec 16, 2005
filing date -
Dec 17, 2004
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Abandoned
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Abstract
The present invention relates to a purified soluble HLA-E molecule, characterized in that: it is a monomeric protein, it presents a sequence identity of at least 80% with membrane-bound HLA-E (SEQ ID NO: 1), it has a molecular weight from about 36 kDa to about 42 kDa, it binds to the CD94/NKG2A receptor.
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