PREVENTIVE OR THERAPEUTIC AGENT FOR CEREBRAL ISCHEMIC INJURY OR CEREBRAL ISCHEMIA REPERFUSION IN STROKE

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United States of America Patent

SERIAL NO

12195084

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides a preventive or therapeutic agent for cerebral ischemic injury or cerebral ischemic reperfusion injury in stroke such as cerebral infarction and cerebral hemorrhage which exerts its effect through a different mechanism from that of conventional therapeutic agents and can be taken for along period. The present invention is a preventive or therapeutic agent for cerebral ischemic injury or cerebral ischemic reperfusion injury in stroke which contains 6-fluoro-2′,5′-dioxospiro[chroman-4,4′-imidazolidine]-2-carboxamide as an active ingredient. A particularly preferable compound is an optically resolved (2S,4S)-form of fidarestat.

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Patent Owner(s)

Patent OwnerAddress
SANWA KAGAKU KENKYUSHO CO LTD35 HIGASHISOTOBORI-CHO HIGASHI-KU NAGOYA-SHI AICHI 4618631 ?4618631

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHUNG, Sookja Kim Hong Kong, CN 3 6
CHUNG, Stephen Hong Kong, CN 46 462
HIBI, Chihiro Aichi, JP 6 11

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