Dendritic cell stimulatory factor

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United States of America Patent

SERIAL NO

12187575

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Abstract

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Flt3-ligand can be used to generate large numbers of dendritic cells from hematopoietic progenitor and stem cells. Flt3-ligand can be used to augment immune responses in vivo, and expand dendritic cells ex vivo. Such dendritic cells can then be used to present tumor, viral or other antigens to naive T cells, can be useful as vaccine adjuvants.

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Patent Owner(s)

Patent OwnerAddress
CELLDEX THERAPEUTICS INC119 FOURTH AVENUE NEEDHAM MA 02494-2725

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BRASEL, Kenneth Seattle , US 7 19
Lyman, Stewart D Seattle , US 38 273
Lynch, David H Bainbridge Island , US 18 213
Maliszewski, Charles R Seattle , US 21 186
Maraskovsky, Eugene Seattle , US 31 363
McKenna, Hilary R Seattle , US 2 5

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