USE OF METHYLATED OR UNMETHYLATED LINE-1 DNA AS A CANCER MARKER
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United States of America Patent
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Issued Date -
Mar 12, 2009
app pub date -
Apr 25, 2008
filing date -
Apr 25, 2007
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Abandoned
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Abstract
The invention relates to a method of detecting LINE-1 (long interspersed nucleotide elements-1) DNA either methylated or unmethylated at the promoter region in a tissue or body fluid sample from a subject. Also disclosed are methods of using LINE-1 DNA as a biomarker for diagnosing, predicting, and monitoring cancer progression and treatment.
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