PLANT VIRAL PARTICLES COMPRISING A PLURALITY OF FUSION PROTEINS CONSISTING OF A PLANT VIRAL COAT PROTEIN, A PEPTIDE LINKER AND A RECOMBINANT PROTEIN AND USE OF SUCH PLANT VIRAL PARTICLES FOR PROTEIN PURIFICATION
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United States of America Patent
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Issued Date -
Mar 5, 2009
app pub date -
Sep 15, 2006
filing date -
Sep 17, 2005
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Abandoned
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Abstract
A process of purifying a protein of interest using viral particles or virus-like particles comprising a plurality of fusion protein molecules, said fusion protein comprising the following fusion protein domains: (i) a plant viral coat protein, (ii) a recombinant protein, and (iii) optionally a peptide linker linking said plant viral coat protein and said recombinant protein, wherein formation of said viral particle does not require free viral coat protein.
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