Lupane-Type Triterpenoids Modified at 30-Position and Analogues Thereof
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United States of America Patent
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Issued Date -
Mar 5, 2009
app pub date -
Jul 10, 2008
filing date -
Aug 3, 2007
priority date (Note) -
Abandoned
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Abstract
The present invention comprises lupine-type triterpenoids that inhibit cell proliferations, in particular cancer and conditions associated with cancer. For example, associated malignancies include ovarian cancer, cervical cancer, breast cancer, colorectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases. Thus, the present invention also comprising pharmaceutical formulations comprising the compounds and methods of using the compounds and formulations to inhibit cancer and treat, prevent, or inhibit the foregoing diseases.
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