MICROFLUIDIC APPARATUS AND METHOD FOR SAMPLE PREPARATION AND ANALYSIS
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United States of America Patent
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Issued Date -
Feb 26, 2009
app pub date -
Aug 10, 2006
filing date -
Aug 11, 2005
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Abandoned
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Abstract
The pumps (Pn) are operated to transport individual reagent streams into the chip in a non-pulsatile, laminar flow regime at low flow rates permitting lows grading from 0 to as little as 5 nl/min with a precision of 0.1 nl/min. In the chip (MFC), the reagent streams are merged and the reagents mixed to form a reaction product. The reaction product can be measured at one or more detection points defined in the chip. Concentration gradients are continuously varied by continuously varying the flow rates respectively produced by the pumps according to predetermined flow velocity profiles.
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