Pharmaceutical composition for obstructive vascular disease
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United States of America Patent
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Issued Date -
Feb 19, 2009
app pub date -
May 24, 2006
filing date -
May 25, 2005
priority date (Note) -
Abandoned
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Abstract
Provided is the excellent prevention or treatment of a vascular occlusive disease such as vascular restenosis. A pharmaceutical composition for a obstructive vascular disease comprising a nucleic acid construct capable of inhibiting the expression of a midkine gene through RNA interference and a collagen molecule. The use of the nucleic acid construct capable of inhibiting the expression of an MK protein through RNA interference in the presence of the collagen molecule can provide an excellent inhibitory effect on the thickened vascular intima.
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