PHTHALAZINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME
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United States of America Patent
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Issued Date -
Feb 12, 2009
app pub date -
Apr 21, 2006
filing date -
Apr 21, 2005
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Abandoned
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Abstract
The present invention provides a novel compound having an excellent PDE4 inhibitory activity and TNF-α production-suppressing activity, and also provides a preventive and therapeutic agent for atopic dermatitis or the like. The present invention includes a novel phthalazinone derivative of the following general structural formula [1] or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising it as an active ingredient.represent alkyl or the like.
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