Heterobifunctional compounds for selectin inhibition
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United States of America Patent
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Issued Date -
Feb 5, 2009
app pub date -
May 24, 2006
filing date -
May 25, 2005
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Abandoned
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Abstract
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise glycomimetics linked to a compound, for example a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids) or a member of a class of compounds termed BACAs (Benzyl Amino Carboxylic Acids).
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