Method for Evaluating Compound Using Barlp and Substance for Regulating Eating and Body Weight
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United States of America Patent
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Issued Date -
Jan 22, 2009
app pub date -
Apr 25, 2006
filing date -
Apr 26, 2005
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Abandoned
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Abstract
It is intended to provide a method for evaluating a compound which regulates eating or body weight characterized by comprising the steps of introducing a BARLP gene and preparing a cell expressing BARLP; bringing a test compound into contact with the cell; and detecting a specific binding of the test compound to the BARLP and a method for evaluating a compound further comprising the step of evaluating a test compound using a nonhuman genetically-engineered animal in which the BARLP gene is inactivated. According to this invention, knowledge about a relationship between BARLP and biological functions is obtained and a method for evaluating a compound targeting BARLP and a BARLP ligand obtained by the evaluation can be provided.
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