RANK LIGAND-BINDING POLYPEPTIDES
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United States of America Patent
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app pub date -
Nov 19, 2007
filing date -
Feb 9, 2001
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Abstract
The present invention relates to a polypeptide having an amino acid sequence that differs from and is at least 70% identical to the amino acid sequence of hRANK, and which has a binding affinity to RANKL that is at least as high as the binding affinity of hRANK to RANKL, as determined by the functional competition assay described herein.
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