Alzheimer's Disease Examination Method
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United States of America Patent
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Issued Date -
Jan 15, 2009
app pub date -
Dec 26, 2005
filing date -
Dec 28, 2004
priority date (Note) -
Abandoned
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Abstract
[Problems] To enable convenient and accurate examination of Alzheimer's disease.[Means for Solving Problems] A reaction liquor, which is prepared by mixing an amyloid β protein with a body fluid collected from a subject and a buffer solution is reacted. After the polymerization of the amyloid β protein comes to equilibrium, the degree of the amyloid β protein polymerization is examined. For example, the above-described reaction liquor is mixed with a fluorescent dye after the completion of the reaction and the degree of the color-development of the reaction liquor is detected to thereby examine the degree of the amyloid β protein polymerization. The fluorescent dye as described above is thioflavin T or its derivative. The body fluid as described above is cerebral fluid, blood or a blood component.
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