METHOD AND DEVICE FOR THE CRYO-CONSERVATION OF SAMPLES
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United States of America Patent
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Issued Date -
Jan 8, 2009
app pub date -
Jul 1, 2008
filing date -
Jul 6, 2007
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Abandoned
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Abstract
A method and a device for the cryo-conservation of a hydrous sample, in particular biological sample, wherein the sample is introduced into a cavity of a container, remaining free space of the cavity if any is filled with a hydrous liquid, the cavity is closed in a liquid-tight manner and the container is held in a holding device, and the container together with the sample is cooled to a temperature below 251 K, preferably 173 K, for example by means of liquid nitrogen, propane or ethane, wherein the container and the holding device prevent an expansion of the cavity in volume. The selected cooling rate is sufficiently high so that a crystal formation of the freezing water is suppressed in favor of glass formation.
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