FUNCTIONAL TOLL-LIKE RECEPTORS (TLR) ON MELANOCYTES AND MELANOMA CELLS AND USES THEREOF

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United States of America Patent

APP PUB NO 20090011418A1
SERIAL NO

12109295

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a method of detecting Toll-like receptor (TLR) gene expression or protein activity in a melanocyte or melanoma cell. Also disclosed are a method of modulating TLR gene expression or protein activity in a melanocyte or melanoma cell by contacting the cell with a TLR modulating agent and a method of inhibiting melanoma cell migration (e.g., spreading) by contacting the cell with a TLR inhibitor.

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Patent Owner(s)

Patent OwnerAddress
JOHN WAYNE CANCER INSTITUTE2200 SANTA MONICA BOULEVARD ST JOHN SOUTH HEALTH CENTER SANTA MONICA CA 90404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Goto, Yasufumi Santa Monica, US 5 5
HOON, Dave SB Santa Monica, US 48 292

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