Smart Biocatalysts For Organic Synthesis
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United States of America Patent
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Issued Date -
Jan 1, 2009
app pub date -
Jun 26, 2007
filing date -
Jun 26, 2007
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Abandoned
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Abstract
The present disclosure relates to compositions, systems, and methods that include a reusable biocatalyst. A reusable biocatalytic composition may include a stimulus-responsive support operable to be soluble under at least one first condition and insoluble under at least one second condition; and a biocatalyst bound to the stimulus-responsive support complex. According to some embodiments, a method for catalyzing a reaction may include contacting a first reactant with a composition comprising a stimulus-responsive support, a biocatalyst linked to the stimulus-responsive support, and a first solvent under conditions in which the stimulus-responsive support is soluble in the solvent and the reactant is converted to a product. A reusable biocatalyst system, in some embodiments, may include (a) a stimulus-responsive support; (b) a biocatalyst (i) bound to the stimulus-responsive support complex and (ii) having catalytic activity in the presence of a substrate; and a solvent operable to support both first and second condition.
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