COMBINATION THERAPY USING ACTIVE IMMUNOTHERAPY
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United States of America Patent
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Issued Date -
Jan 1, 2009
app pub date -
Mar 25, 2008
filing date -
Mar 26, 2007
priority date (Note) -
Abandoned
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Abstract
The present invention relates to methods of treating cancer in a mammal comprising administering to the mammal a combination therapy comprising a vaccine and a multi-kinase inhibitor, wherein the vaccine comprises an isolated tumor associated peptide having the ability to bind to a molecule of the human major histocompatibility complex (MHC) class-I or class-II. Preferably the multi-kinase inhibitor is sunitinib malate and/or sorafenib tosylate or a pharmaceutically acceptable salt thereof.
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