Use of Sirnas in Organ Storage/Reperfusion Solutions

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United States of America Patent

APP PUB NO 20080311552A1
SERIAL NO

12067542

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention is the modification of organs, tissues and cells with a storage/reperfusion solution comprising siRNAs specific for genes whose expression is associated with loss of viability or cell damage. The presence of siRNAs in the storage/reperfusion solution minimizes and/or prevents organ, tissue and cell damage such that the organs, tissues or cells can be used for in vivo transplantation. The invention is also directed generally to methods for maintaining organs, tissues and cells in a viable state using the storage/reperfusion solution.

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Patent Owner(s)

Patent OwnerAddress
LONDON HEALTH SCIENCES CENTRE RESEARCH INCLONDON ON

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Min, Weiping London, CA 2 44

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  • 24 Citation Count
  • A01N Class
  • 88.44 % this patent is cited more than
  • 17 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges12245910046111073521401 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0255075100125150175200225250275300325350375400425450475500

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