EP4 RECEPTOR ANTAGONISTS

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United States of America Patent

APP PUB NO 20080306117A1
SERIAL NO

12186308

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A compound of formula (I): or a salt, solvate and chemically protected form thereof, wherein one of R.sup.2 and R.sup.5 is: (i) H or an optionally substituted C.sub.1-4 alkyl group; or (ii) an optionally substituted C.sub.5-7 aryl; and the other of R.sup.2 and R.sup.5 is the other group; m and n can be 0 or 1, and m+n=1 or 2 R.sup.N is H or optionally substituted C.sub.1-4 alkyl R.sup.3 is either: (i) carboxy; (ii) a group of formula (II): (iii) a group of formula (III): wherein R is optionally substituted C.sub.1-7 alkyl, C.sub.5-20 aryl, or NR.sup.N3R.sup.N4, where R.sup.N3 and R.sup.N4 are independently selected from optionally substituted C.sub.1-4 alkyl; or (iv) tetrazol-5-yl.

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Patent Owner(s)

Patent OwnerAddress
ASTERAND UK LIMITEDROYSTON HERTFORDSHIRE SG8 5HD

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Clark, David Edward Essex, GB 40 233
Clark, Kenneth Lyle Hertfordshire, GB 16 49
Coleman, Robert Alexander Hertfordshire, GB 15 70
Davis, Richard Jon Hertfordshire, GB 8 69
Fenton, Garry Essex, GB 36 326
Harris, Neil Victor Essex, GB 24 273
Hynd, George Essex, GB 64 241
Oxford, Alexander William Hertfordshire, GB 21 153
Stuttle, Keith Alfred James Essex, GB 11 117
Sutton, Jonathan Mark Essex, GB 37 203

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