SIGNAL AMPLIFICATION USING CIRCULAR HAIRPIN PROBES
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United States of America Patent
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Issued Date -
Dec 11, 2008
app pub date -
May 1, 2008
filing date -
Jun 6, 2007
priority date (Note) -
Abandoned
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Abstract
The present invention provides methods for detecting a target nucleic acid using a circular dual-hairpin probe that is formed upon the presence of the target nucleic acid. The detection methods find use in detecting the presence of antibody-antigen complexes and for detecting the binding of a ligand to its binding partner. Kits and reaction mixtures for performing the present methods are also provided.
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