Polynucleotide for Producing Recombinant Protein in Silkworm
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United States of America Patent
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Issued Date -
Dec 4, 2008
app pub date -
Oct 14, 2005
filing date -
Oct 15, 2004
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Abandoned
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Abstract
As novel means for causing any recombinant protein produced by the silkworm middle silk gland to be secreted in cocoons and easily extracting the recombinant protein from the cocoons without modification of the conformation of the protein, there is provided a polynucleotide that in an expression cassette for expression of a recombinant protein by the silkworm middle silk gland, is functionally linked to a recombinant protein structure gene, which polynucleotide is one composed of a polynucleotide constructing the promoter regions of sericin 1 or sericin 2 gene and, functionally linked thereto, a polynucleotide constructing the homologous regions of baculovirus.
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