Methods of Employing Vascular Leakage to Diagnose a Capillary Leak Disorder
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United States of America Patent
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Issued Date -
Dec 4, 2008
app pub date -
Apr 24, 2008
filing date -
May 31, 2007
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Abstract
A method of diagnosing a capillary leak disorder in a patient includes monitoring the marinobufagenin level in blood and/or urine as indicators of vascular permeability and, if a substantial elevation in marinobufagenin exists with respect to that of a normal person, concluding that a capillary leak disorder exists. The method may be employed to diagnose preeclampsia, as well as illnesses or abnormal conditions selected from the group consisting of acute respiratory distress syndrome, hemorrhagic shock, septic, endotoxemia, septicemia, burns.
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