Combination of Ad-P53 and Chemotherapy for the Treatment of Tumours
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United States of America Patent
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Issued Date -
Nov 27, 2008
app pub date -
Feb 24, 2005
filing date -
Feb 24, 2004
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Abstract
The present invention relates to the use of p53 gene therapy to treat recurrent cancers in combination with a radio- or chemotherapy. Patients with recurring cancers are treated with a p53 expression construct followed by subsequent radio- or chemotherapy treatment. Viral and non-viral delivery systems, as well as various radio- and chemotherapy regimens are disclosed.
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